---
title: "nf-core: Community curated bioinformatics pipelines"
url: "https://phil.ewels.co.uk/publications/2019/ewels-biorxiv"
site: "phil.ewels.co.uk"
author: "Phil Ewels"
section: "Publications"
journal: "bioRxiv"
published: "2019-04-16"
doi: "https://doi.org/10.1101/610741"
authors: "Philip A Ewels, Alexander Peltzer, Sven Fillinger, Johannes Alneberg, Harshil Patel, Andreas Wilm, Maxime Ulysse Garcia, Paolo Di Tommaso, Sven Nahnsen"
---

# nf-core: Community curated bioinformatics pipelines

> **Now published:** this preprint has since been peer-reviewed and published in _Nature Biotechnology_ as [The nf-core framework for community-curated bioinformatics pipelines](https://phil.ewels.co.uk/publications/2020/ewels-nature-biotechnology).

## Abstract

The standardization, portability, and reproducibility of analysis pipelines is a renowned problem within the bioinformatics community. Most pipelines are designed for execution on-premise, and the associated software dependencies are tightly coupled with the local compute environment. This leads to poor pipeline portability and reproducibility of the ensuing results - both of which are fundamental requirements for the validation of scientific findings. Here, we introduce _nf-core_: a framework that provides a community-driven, peer-reviewed platform for the development of best practice analysis pipelines written in Nextflow. Key obstacles in pipeline development such as portability, reproducibility, scalability and unified parallelism are inherently addressed by all _nf-core_ pipelines. We are also continually developing a suite of tools that assist in the creation and development of both new and existing pipelines. Our primary goal is to provide a platform for high-quality, reproducible bioinformatics pipelines that can be utilized across various institutions and research facilities.

---

From the personal website of Phil Ewels, a software developer and bioinformatician in Stockholm, Sweden: https://phil.ewels.co.uk/
The whole site as Markdown: https://phil.ewels.co.uk/llms.txt